Half-lives and Transcriptional Frequencies

Page 13 of 309

Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

BIO5
#N/A
18
#N/A
Transmembrane regulator of KAPA/DAPA transport, involved in biotin biosynthesis

BMH1
16.5
17
35.3
Homolog of mammalian 14-3-3 protein, has strong similarity to Bmh2p

BMH2
4.6
20
8.7
Homolog of mammalian 14-3-3 protein, has strong similarity to Bmh1p

BNI1
0.8
26
1.2
Protein that interacts with Rho1p; involved in cytoskeletal control and required for proper bipolar budding pattern

BNI4
0.6
13
1.5
Protein that may be involved in linking chitin synthase III to septins of the neck filaments

BNR1
0.2
22
0.4
Bni1p-related protein, potential target of Rho4p

BOI1
1.5
15
3.6
Bem1p-binding protein, has a SH3 domain and a PH (pleckstrin) domain

BOI2
0.6
14
1.4
Protein with SH3 domain involved in bud formation, binds to Bem1p

BOS1
1.6
14
4.1
Synaptobrevin (v-SNARE) homolog involved in ER to Golgi transport

BPH1
0.2
#N/A-nc
#N/A
Probable acetic acid export pump; has WD (WD-40) repeats in the C-terminal domain

BPL1
0.7
15
1.7
Biotin holocarboxylase synthetase,

BRF1
1.2
14
3.3
Transcription factor IIIB, 70K subunit

BRN1
#N/A
#N/A-nc
#N/A
Protein involved in chromsome maintenance

BRO1
0.6
23
0.9
Protein that interacts with components of the PKC1-MAP kinase pathway

BRR1
0.8
16
1.8
Protein involved in snRNP biogenesis

BRR2
0.4
30
0.6
RNA helicase-related protein required for pre-mRNA splicing

BSD2
1.2
44
1
Metal homeostasis protein

BST1
0.4
24
0.7
Protein that negatively regulates COPII vesicle formation

BTS1
0.4
17
0.9
Geranylgeranyl diphosphate synthase

BTT1
0.2
#N/A-nc
#N/A
Protein with a negative role in expression of GAL genes and other RNA polymerase II transcribed genes; has strong similarity to Egd1p and to human BTF3 protein

Gene	Expression Level (Copies/Cell)	mRNA Half-life (min)	Transcriptional Frequency (mRNAs/hr)	YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]
BIO5	#N/A	18	#N/A	Transmembrane regulator of KAPA/DAPA transport, involved in biotin biosynthesis
BMH1	16.5	17	35.3	Homolog of mammalian 14-3-3 protein, has strong similarity to Bmh2p
BMH2	4.6	20	8.7	Homolog of mammalian 14-3-3 protein, has strong similarity to Bmh1p
BNI1	0.8	26	1.2	Protein that interacts with Rho1p; involved in cytoskeletal control and required for proper bipolar budding pattern
BNI4	0.6	13	1.5	Protein that may be involved in linking chitin synthase III to septins of the neck filaments
BNR1	0.2	22	0.4	Bni1p-related protein, potential target of Rho4p
BOI1	1.5	15	3.6	Bem1p-binding protein, has a SH3 domain and a PH (pleckstrin) domain
BOI2	0.6	14	1.4	Protein with SH3 domain involved in bud formation, binds to Bem1p
BOS1	1.6	14	4.1	Synaptobrevin (v-SNARE) homolog involved in ER to Golgi transport
BPH1	0.2	#N/A-nc	#N/A	Probable acetic acid export pump; has WD (WD-40) repeats in the C-terminal domain
BPL1	0.7	15	1.7	Biotin holocarboxylase synthetase,
BRF1	1.2	14	3.3	Transcription factor IIIB, 70K subunit
BRN1	#N/A	#N/A-nc	#N/A	Protein involved in chromsome maintenance
BRO1	0.6	23	0.9	Protein that interacts with components of the PKC1-MAP kinase pathway
BRR1	0.8	16	1.8	Protein involved in snRNP biogenesis
BRR2	0.4	30	0.6	RNA helicase-related protein required for pre-mRNA splicing
BSD2	1.2	44	1	Metal homeostasis protein
BST1	0.4	24	0.7	Protein that negatively regulates COPII vesicle formation
BTS1	0.4	17	0.9	Geranylgeranyl diphosphate synthase
BTT1	0.2	#N/A-nc	#N/A	Protein with a negative role in expression of GAL genes and other RNA polymerase II transcribed genes; has strong similarity to Egd1p and to human BTF3 protein

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