Half-lives and Transcriptional Frequencies

Page 142 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

UBC12

0.2

18

0.4

Rub1p-conjugating enzyme, with similarity to ubiquitin- and ubiquitin-like protein-conjugating enzymes

UBC13

3.1

14

8.4

Ubiquitin-conjugating enzymes

UBC4

9.7

24

14.9

Ubiquitin-conjugating enzyme that with Ubc5p is responsible for most of ubiquitin-dependent protein degradation of short-lived and abnormal proteins

UBC5

0.6

69.5

0.4

Ubiquitin-conjugating enzyme that with Ubc4p is responsible for most of ubiquitin-dependent protein degradation of short-lived and abnormal proteins

UBC6

1.6

17

3.3

Ubiquitin-conjugating enzyme anchored in the ER membrane with catalytic activity facing into cytoplasm

UBC7

1.7

22

3

Ubiquitin-conjugating enzyme; associates with Ubc6p on the cytoplasmic side of endoplasmic reticulum

UBC8

0.8

40

0.7

Ubiquitin-conjugating enzyme that is able to ubiquitinate histones in vitro

UBC9

2.9

13

8.2

Smt3p-conjugating enzyme required for G2/M transition

UBI4

2.5

22

4.1

Ubiquitin, mature protein is cleaved from polyubiquitin (Ubi4p) or from fusions with ribosomal proteins

UBP1

3.5

14

9

Ubiquitin-specific protease (ubiquitin C-terminal hydrolase), cleaves at the C-terminus of ubiquitin

UBP11

0.2

30

0.3

Ubiquitin-specific protease

UBP12

0.6

16

1.3

Ubiquitin-specific protease

UBP13

0.6

14

1.6

Ubiquitin C-terminal hydrolase

UBP14

0.7

16

1.7

Ubiquitin-specific protease

UBP2

1.3

20

2.4

Ubiquitin-specific protease (ubiquitin C-terminal hydrolase), cleaves at the C-terminus of ubiquitin

UBP3

0.9

27

1.3

Ubiquitin-specific protease

UBP5

0.6

26

0.7

Ubiquitin-specific protease (ubiquitin C-terminal hydrolase), homologous to Doa4p and human Tre-2

UBP7

0.6

#N/A-nc

#N/A

Putative ubiquitin-specific protease

UBP9

0.1

#N/A-nc

#N/A

Ubiquitin C-terminal hydrolase, has similarity to Ubp13p

UBR1

0.7

30

0.8

Ubiquitin-protein ligase (N-recognin or E3 enzyme), involved in selection of substrates for the N-end rule pathway

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