Half-lives and Transcriptional Frequencies

Page 143 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

UBS1

0.9

26

1.2

Positive regulator of Cdc34p

UFD1

0.4

20

0.9

Ubiquitin fusion degradation protein

UFD2

1.8

55

1.2

Ubiquitin fusion degradation protein

UFD4

1.2

48

0.9

Probable ubiquitin-protein ligase (E3 enzyme) functioning in ubiquitin fusion degradation pathway

UFE1

0.6

19

1

Syntaxin homolog (t-SNARE) of the endoplasmic reticulum required for targeting of vesicles to the ER

UGA1

0.9

16

1.9

4-Aminobutyrate aminotransferase (GABA transaminase), produces gamma-aminobutyric acid

UGA3

0.3

30

0.4

Transcriptional activator for 4-aminobutyric acid (GABA) catabolic genes, including UGA4, UGA1, and UGS2

UGA4

0.3

17

0.8

High-affinity permease with specificity for 4-aminobutyric acid (GABA)

UGP1

5.5

31

6.5

UDP-glucose pyrophosphorylase (UTP-glucose-1-P uridylyltransferase)

UGX2

#N/A

30

#N/A

Protein of unknown function

ULA1

0.4

19

0.9

Rub1-activating enzyme, similar to ubiquitin-activating E1-like proteins

UME1

0.8

14

2.2

Negative regulator of meiosis

UME6

0.3

17

0.7

Negative transcriptional regulator involved in nitrogen repression and induction of meiosis

UMP1

1.6

20

2.9

Proteasome maturation factor, chaperone involved in proteasome assembly

UNG1

0.7

10

2.5

Uracil-DNA glycolyase, removes uracil from DNA

UPF3

0.6

23

0.9

Protein involved with Nam7p and Nmd2p in decay of mRNA containing nonsense codons

URA1

16.2

8

71.9

Dihydroorotate dehydrogenase, fourth step in pyrimidine biosynthesis pathway

URA10

0.2

15

0.5

Orotate phosphoribosyltransferase 2, fifth step in pyrimidine biosynthesis pathway

URA2

8.2

15

19.7

Multifunctional pyrimidine biosynthesis protein (contains glutamine amidotransferase, glutamine-dependent carbamylphosphate synthase (CPSase) and aspartate carbamyltransferase

URA3

0.7

44

0.6

Orotidine-5'-phosphate decarboxylase

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The most up-to-date information on these proteins can be found by clicking on the protein name or going to http://www.proteome.com/databases/index.html.

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