Half-lives and Transcriptional Frequencies

Page 146 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

VPS1

1.2

17

2.8

Vacuolar sorting protein, member of the dynamin family of GTPases

VPS13

0.9

#N/A-se

#N/A

Protein involved in vacuolar sorting

VPS15

0.3

17

0.8

Serine/threonine protein kinase involved in vacuolar protein sorting

VPS16

0.2

14

0.5

Vacuolar sorting protein, mutant has pleiotropic defects in vacuolar morphology and vacuolar protein targeting

VPS17

0.7

31

0.7

Peripheral membrane protein required for vacuolar protein sorting, mutant has fragmented vacuoles

VPS21

2.4

17

5.1

GTP-binding protein of the rab family required for sorting of vacuolar proteins and involved in late stage of endocytosis

VPS24

0.8

18

1.6

Protein involved in sorting of vacuolar hydrolases through the secretory system

VPS27

0.4

24

0.6

Protein involved in vacuolar sorting, mutant has a prominent novel pre-vacuolar organelle

VPS28

0.6

15

1.5

Protein required for traffic to the vacuole through the endocytic and biosynthetic pathways

VPS3

0.3

27

0.5

Vacuolar sorting protein, also involved in vacuolar segregation

VPS30

0.4

24

0.7

Protein involved in sorting and delivery of soluble hydrolases to the vacuole

VPS33

0.4

22

0.7

Vacuolar sorting protein of the Sec1p family, essential for vacuolar morphogenesis and function

VPS34

0.6

24

0.8

Phosphatidylinositol 3-kinase (PI kinase) required for vacuolar protein sorting, activated by protein kinase Vps15p

VPS35

0.9

15

2.1

Protein involved in vacuolar sorting, mutant has vacuoles of normal morphology

VPS36

0.3

20

0.6

Protein involved in vacuolar sorting, mutant has a prominent novel pre-vacuolar organelle

VPS38

0.2

#N/A-nc

#N/A

Protein involved in vacuolar sorting

VPS4

2.2

19

4.4

Protein involved in vacuolar sorting that causes a novel pre-vacuolar organelle to become prominent; has similarity to members of the AAA family

VPS41

0.4

20

0.8

Protein involved in the last step of vaculolar assembly

VPS45

0.6

17

1.3

Protein of the Sec1p family essential for vacuolar protein sorting

VPS5

0.6

17

1.1

Member of the sorting nexin family involved in Golgi retention and vacuolar sorting

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The most up-to-date information on these proteins can be found by clicking on the protein name or going to http://www.proteome.com/databases/index.html.

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