Half-lives and Transcriptional Frequencies

Page 35 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

ERG4

6.6

17

14.2

Sterol C-24 (28) reductase

ERG5

2.1

12

6.3

Cytochrome P450

ERG6

4.3

14

11.3

S-adenosylmethionine delta-24-sterol-C-methyltransferase, carries out methylation of zymosterol as part of the ergosterol biosynthesis pathway

ERG7

1.6

12

4.6

Lanosterol synthase; carries out complex cyclization step of squalene to lanosterol in ergosterol biosynthesis pathway

ERG8

1.1

23

1.8

Phosphomevalonate kinase, converts mevalonate-5-phosphate to mevalonate pyrophosphate, involved in isoprene and ergosterol biosynthesis pathways

ERG9

4.0

21

7.2

Squalene synthetase (farnesyl-diphosphate farnesyltransferase), acts at a branch point in the isoprenoid biosynthesis pathway

ERO1

2.0

30

2.5

Protein required for protein disulfide bond formation in the endoplasmic reticulum

ERR1

#N/A

23

#N/A

Enolase-related subtelomeric sequence (see R316)

ERR2

#N/A

#N/A-nc

#N/A

Enolase-related subtelomeric sequence

ERS1

0.8

25

1.2

Suppressor of erd1 mutation

ERV1

2.1

12

6.4

Protein essential for mitochondrial biogenesis and cell viability

ERV25

13.2

20

24.7

Component of the COPII coat of certain ER-derived vesicles

ESBP6

1.0

21

1.8

Protein with similarity to mammalian monocarboxylate transporters MCT1 and MCT2

ESC2

0.3

18

0.8

Protein involved in chromatin silencing

ESC4

0.6

12

1.8

Protein involved in chromatin silencing

ESC5

0.4

15

1.2

Protein involved in chromatin silencing, has similarity to Tof2p

ESP1

0.6

#N/A-nc

#N/A

Protein involved in regulation of spindle pole body duplication

ESS1

2.0

18

4.2

Processing/termination factor, involved in transcription termination or 3'-end processing of pre-mRNA

EST1

0.2

15

0.6

Putative component of telomerase

EST2

0.2

15

0.5

Catalytic component of telomerase, has similarity to reverse transcriptase

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The most up-to-date information on these proteins can be found by clicking on the protein name or going to http://www.proteome.com/databases/index.html.

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