Half-lives and Transcriptional Frequencies

Page 47 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

HAT2

1.5

14

4

Histone acetyltransferase subunit 2; contains 7 WD (WD-40) repeats

HBS1

1.3

15

3.3

Protein related to translation elongation factor EF-1alpha and to Sup35p

HCA4

0.4

8

2.1

Probable RNA helicase CA4, involved in ribosomal RNA processing

HCM1

0.7

23

1

Dosage-dependent suppressor of cmd1 and member of the forkhead family of DNA-binding proteins

HCS1

0.2

#N/A-nc

#N/A

DNA helicase A and Dom34p-interacting protein (47, 2652, 2655, 32404, 32405

HCT1

0.3

#N/A-nc

#N/A

Protein involved in Clb2p cyclin proteolysis, has WD (WD-40) repeats

HDA1

0.7

13

2

Component of histone deacetylase A, 75 kDa subunit

HDF1

0.3

23

0.5

Component of DNA end-joining repair pathway; acts in complex with Hdf2p

HDF2

0.1

#N/A-nc

#N/A

Component of DNA end-joining repair pathway, acts in complex with Hdf1p

HDR1

0.1

#N/A-nc

#N/A

Protein involved in meiotic segregation

HEM1

1.7

12

5.1

5-Aminolevulinate synthase, first step in heme biosynthesis pathway

HEM12

1.5

12

4.4

Uroporphyrinogen decarboxylase, carries out sequential decarboxylation of 4 acetyl side chains of uroporphyrinogen to yield coproporphyrinogen

HEM13

1.2

11

4.1

Coproporphyrinogen III oxidase, oxygen-repressed, sixth step in heme biosynthetic pathway

HEM14

0.4

15

1.1

Protoporphyrinogen oxidase

HEM15

2.0

12

6.3

Ferrochelatase (protoheme ferrolyase), last step in heme biosynthesis pathway, catalyzes insertion of ferrous iron into protoporphyrin IX

HEM2

2.7

16

6.1

Porphobilinogen synthase (delta-aminolevulinic acid dehydratase), second step in heme biosynthesis pathway

HEM3

0.3

#N/A-nc

#N/A

Phorphobilinogen deaminase (pre-uroporphyrinogen synthase), third step in porphyrin biosynthesis pathway

HEM4

0.6

18

1.1

Uroporphyrinogen III synthase, fourth step in heme biosynthesis pathway

HES1

0.1

15

0.4

Protein implicated in ergosterol biosynthesis, member of the KES1/HES1/OSH1/YKR003W family of oxysterol-binding (OSBP) proteins

HEX3

0.3

21

0.5

Protein involved in hexose metabolism

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