Half-lives and Transcriptional Frequencies

Page 60 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

LEU2

3.3

10

11.7

3-Isopropylmalate dehydrogenase, third step in the leucine biosynthesis pathway

LEU3

0.4

13

1.3

Transcription factor regulating genes of branched chain amino acid biosynthesis pathways, acts as both a repressor and an inducer

LEU4

3.6

17

7.7

2-Isopropylmalate synthase, first step in leucine biosynthesis pathway

LHP1

4.4

11

15

Protein homolog to human La autoantigen which binds to and stabilizes pre-tRNA for 3' endonucleolytic cleavage, has an RNA recognition (RRM) domain

LHS1

0.8

12

2.5

Hsp70 superfamily member required for efficient translocation of protein precursors across the ER membrane

LIP5

1.5

17

3.3

Lipoic acid synthase, mutants cannot synthesize lipoic acid, but can attach lipoic acid to protein

LOS1

1.0

13

3.1

Transport receptor for tRNA, member of the karyopherin-beta family

LPD1

2.5

22

4.2

Dihydrolipoamide dehydrogenase; (E3) component of pyruvate dehydrogenase complex, 2-oxoglutarate complex, and branched chain 2-oxoacid dehydrogenase

LPP1

0.6

15

1.5

Lipid phosphate phosphatase, Mg2+-independent

LRE1

0.2

#N/A-se

#N/A

Protein involved in laminarinase resistance

LRG1

0.2

14

0.7

GTPase-activating protein of the rho/rac family, expressed highest in sporulating cells

LRS4

0.2

23

0.4

Protein involved in rDNA silencing

LSC1

1.3

25

2.1

Alpha subunit of succinyl-CoA synthetase (succinyl-CoA ligase) (succinate thiokinase)

LSC2

1.5

16

3.5

Beta subunit of succinyl-CoA synthetase (succinyl-CoA ligase) (succinate thiokinase)

LST7

1.2

20

2.2

Protein required for regulated transport of nitrogen-regulated permeases from the Golgi to the plasma membrane

LST8

2.0

28

2.8

Protein required for transport of permeases from the Golgi to the plasma membrane

LTE1

0.2

15

0.4

GDP/GTP exchange factor

LTP1

1.2

20

2.3

Protein tyrosine phosphatase (PTPase) with similarity to a phosphatase from bovine heart and human placenta

LTV1

0.7

15

1.6

Protein required for viability at low temperature

LYP1

5.4

15

13.5

Lysine-specific permease, high affinity

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The most up-to-date information on these proteins can be found by clicking on the protein name or going to http://www.proteome.com/databases/index.html.

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