Half-lives and Transcriptional Frequencies

Page 14 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

BUB1

0.1

23

0.2

Serine/threonine protein kinase and checkpoint protein required for cell cycle arrest in response to loss of microtubule function

BUB2

0.3

13

1

Checkpoint protein required for cell cycle arrest in response to loss of microtubule function

BUB3

0.9

15

2.2

Checkpoint protein required for cell cycle arrest in response to loss of microtubule function

BUD2

0.2

17

0.5

GTPase-activating protein for Rsr1p/Bud1p involved in bud site selection

BUD3

0.2

27

0.3

Protein localized at the neck filament ring required for axial budding, may provide a memory of the previous bud site

BUD4

0.6

23

1

Protein required for formation of axial but not bipolar budding pattern

BUD5

0.1

23

0.2

GTP/GDP exchange factor for Rsr1p/Bud1p involved in bud site selection, mutants bud at random sites

BUD6

0.4

11

1.6

Protein required for bipolar budding; mutant strains bud randomly

BUD7

0.7

19

1.4

Protein required for bipolar budding pattern

BUD8

0.3

15

0.9

Protein required for bipolar budding, has an RNA recognition (RRM) domain

BUD9

0.3

12

1.1

Protein required for bipolar budding; mutant diploid strains bud only at distal pole

BUL1

0.6

21

1

Protein involved in the ubiquitination pathway

BUR2

0.9

20

1.6

Protein of unknown function

BUR6

3.1

12

9.2

Alpha subunit of NC2 (Dr1/Drap1) repressor of class II transcription

CAC2

0.7

16

1.4

Chromatin assembly complex subunit 1, involved in nucleosome assembly linked with DNA replication, has WD (WD-40) repeats

CAD1

0.3

18

0.6

Transcriptional activator of the basic leucine zipper (bZIP) family, involved in multidrug resistance

CAF16

2.5

17

5.3

Protein that associates with Ccr4p, member of ATP-binding cassette (ABC) superfamily

CAF17

0.6

22

0.9

Component of the CCR4 complex

CAF20

7.3

16

16.6

mRNA cap-binding protein (eIF4F) 20K subunit

CAF4

0.4

13

1.2

Protein that associates with Ccr4p, has WD (WD-40) repeats

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The most up-to-date information on these proteins can be found by clicking on the protein name or going to http://www.proteome.com/databases/index.html.

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