Half-lives and Transcriptional Frequencies

Page 141 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

TSA1

24.9

15

62.7

Thiol-specific antioxidant, abundant protein that protects against sulfur-containing radicals

TSL1

1.3

27

1.9

Component of the trehalose-6-phosphate synthase/phosphatase complex, alternate third subunit with Tps3p

TSM1

0.9

42

0.8

Component of TAF(II) complex (TBP-associated protein complex) required for activated transcription by RNA polymerase II

TSP1

0.8

14

2.1

Transcriptional coactivator, may be involved in the release of TFIIB from the transcription complex during transcription initiation

TTP1

1.2

12

3.7

Protein of unknown function, probable type II integral membrane protein

TTR1

3.4

22

5.6

Glutaredoxin (thioltransferase) (glutathione reductase)

TUB1

2.6

15

6.1

Tubulin alpha-1 chain, required for mitosis and karyogamy

TUB2

6.5

20

11.8

Tubulin beta chain, required for mitosis and karyogamy

TUB3

3.5

21

6.2

Tubulin alpha-3 chain, non-essential

TUB4

0.4

#N/A-nc

#N/A

Gamma tubulin, required for microtubule organization and nuclear division

TUF1

7.2

13

20.3

Translation elongation factor Tu, mitochondrial

TUP1

2.1

21

3.9

General repressor of transcription (with Ssn6p), member of WD (WD-40) repeat family

TWF1

0.6

30

0.6

Twinfilin A, member of a family of proteins that sequester actin monomers

TYE7

1.9

16

4.5

Basic helix-loop-helix transcription factor that can suppress the Gcr1p requirement for glycolytic gene expression

TYR1

1.1

14

3.2

Prephenate dehydrogenase (NADP+), step of tyrosine biosynthesis pathway

TYS1

4.5

26

6.3

Tyrosyl-tRNA synthetase

UBA1

3.4

21

5.8

Ubiquitin-activating enzyme

UBA2

1.1

15

2.7

Subunit of a heterodimeric enzyme consisting of Uba2p and Aos1p, activates the ubiquitin-like Smt3p for conjugation to other proteins

UBA3

0.2

13

0.7

Rub1-activating enzyme, similar to ubiquitin-activating E1-like proteins

UBC1

4.9

23

8

Ubiquitin conjugating enzyme (E2) that plays a role early in spore germination

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The most up-to-date information on these proteins can be found by clicking on the protein name or going to http://www.proteome.com/databases/index.html.

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