Half-lives and Transcriptional Frequencies

Page 144 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

URA4

4.0

9

17

Dihydroorotase, third step in pyrimidine biosynthesis pathway

URA5

12.7

15

30.9

Orotate phosphoribosyltransferase 1, fifth step in pyrimidine biosynthesis pathway

URA6

2.6

17

5.6

Uridine-monophosphate kinase (uridylate kinase), converts ATP and UMP to ADP and UDP

URA7

6.6

11

23.1

CTP synthase, final step in pyrimidine biosynthesis pathway

URA8

0.8

16

2

CTP synthase, last step in pyrimidine biosynthesis pathway

URE2

1.8

17

3.9

Nitrogen catabolite repression regulator which acts by inhibition of the Gln3p regulator in the presence of preferred nitrogen sources

URK1

1.1

12

3.4

Uridine kinase, converts ATP and uridine to ADP and UMP

USO1

0.7

15

1.8

Coiled-coil protein with similarity to mammalian integrin, required for protein transport from ER to Golgi

USS1

1.7

20

3.2

UTH1

22.3

28

29.2

Protein involved in the aging process, mutants have longer lifespan and better viability upon starvation

UTR1

1.3

21

2.4

Protein that may be associated with ferric reductase activity

UTR2

14.1

12

44.1

Protein of unknown function

UTR3

0.3

11

1.3

Protein of unknown function

UTR4

2.9

16

6.9

Protein of unknown function

UTR5

#N/A

#N/A-nc

#N/A

Protein of unknown function

VAC7

0.2

13

0.8

Integral vacuolar membrane protein, involved in vacuole morphology and inheritance

VAC8

1.6

21

2.7

Vacuolar protein involved in vacuolar inheritance and protein targeting from the cytoplasm to vacuole

VAM3

1.2

13

3.6

Syntaxin homolog (t-SNARE), required for vacuolar assembly

VAM6

0.3

15

0.9

Protein involved in the last step of vacuolar assembly

VAM7

0.2

#N/A-nc

#N/A

Protein involved in morphogenesis of the vacuole, SNAP-25 homolog, part of vacuolar SNARE complex

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The most up-to-date information on these proteins can be found by clicking on the protein name or going to http://www.proteome.com/databases/index.html.

Genome-wide Expression Page