Half-lives and Transcriptional Frequencies

Page 56 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

ITR1

5.2

9

20.2

Myo-inositol permease (major), closely related to Itr2p

ITR2

2.5

13

7.3

Myo-inositol permease (minor), closely related to Itr1p

IXR1

0.6

#N/A-nc

#N/A

Intrastrand crosslink recognition protein with 2 HMG boxes and transcription factor that confers oxygen (O2) regulation on COX5B

JA2

0.8

14

2

RNA helicase of DEAH box family, possible pre-mRNA splicing factor

JAC1

#N/A

#N/A-nc

#N/A

Homolog of E. coli Hsc20 co-chaperonin

JEM1

0.4

22

0.7

DnaJ-like protein, required for nuclear fusion

JEN1

0.3

16

0.8

Protein with similarity to E. coli osmoregulatory proP proline/betaine transporter and KgtP alpha-ketoglutarate transporter, member of the major facilitator superfamily

JNM1

0.4

15

1.2

Coiled-coil protein involved in nuclear migration and control of astral microtubules during mitotic growth

JSN1

0.7

25

1.1

Protein that when overexpressed can suppress the hyperstable microtubule phenotype of tub2-150

KAP104

0.8

16

1.9

Transportin, beta-karyopherin involved in nuclear transport of mRNA-binding proteins

KAP121

6.1

14

15.8

Beta-Karyopherin; involved in nuclear import of ribosomal proteins

KAP123

1.9

13

5.4

Karyopherin-beta, involved in nuclear import of ribosomal proteins

KAP95

1.1

21

2.1

Karyopherin-beta; acts to target proteins with nuclear localization (NLS) sequences to the nuclear pore complex

KAR1

1.0

10

3.4

Protein required for spindle pole body duplication and karyogamy

KAR2

13.4

20

24.7

Heat shock protein required for protein translocation across the ER membrane; HSP70 family member of the ER lumen and required for nuclear fusion

KAR3

0.3

15

0.8

Kinesin-like protein involved in mitosis and essential for the congression (nuclear migration) step of karyogamy, probable coiled-coil protein

KAR4

1.3

16

3.3

Regulatory protein required for pheromone induction of karyogamy genes

KAR5

0.3

23

0.5

Coiled-coil membrane protein, required for homotypic nuclear fusion

KAR9

#N/A

#N/A-nc

#N/A

Protein of the cell cortex required for the congression (nuclear migration) step of karyogamy, involved in proper orientation of cytoplasmic microtubules

KCS1

1.2

12

4

Potential transcription factor of the basic leucine zipper (bZIP) type, suppressor of temperature-sensitive growth and hyperrecombination in pkc1-4

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The most up-to-date information on these proteins can be found by clicking on the protein name or going to http://www.proteome.com/databases/index.html.

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