Half-lives and Transcriptional Frequencies

Page 61 of 309


Gene

Expression Level
(Copies/Cell)

mRNA Half-life
(min)

Transcriptional
Frequency
(mRNAs/hr)

YPD Title Line™ ©2000 Proteome, Inc. Reprinted with permission. [last updated: 11/23/98]

LYS1

1.3

19

2.7

Saccharopine dehydrogenase (NAD+, L-lysine forming), eighth and last step in lysine biosynthesis pathway

LYS12

4.0

12

12.3

Homoisocitrate dehyrogenase, fourth step in lysine biosynthesis pathway, converts homoisocitrate to alpha-ketoadipate

LYS14

0.4

18

1

Transcriptional activator of lysine pathway genes with 2-aminoadipate semialdehyde as coinducer

LYS2

2.1

19

4.1

Alpha-aminoadipate-semialdehyde dehydrogenase (aminoadipate reductase), sixth step in lysine biosynthesis pathway

LYS20

4.8

11

16.8

Probable homocitrate synthase or isopropylmalate synthase

LYS21

3.0

12

9.6

S.cerevisiae chromosome IV reading frame ORF YDL131w.

LYS4

2.7

16

6.3

Homoaconitate hydratase (homoaconitase), third step in lysine biosynthesis pathway, converts homoaconitate to homoisocitrate

LYS5

0.3

18

0.7

Alpha-aminoadipate reductase small chain, required with Lys2p for aminoadipate reductase activity, member of the heteropolymeric alpha-aminoadipate reductase complex

LYS7

2.6

12

8.5

Copper chaperone for superoxide dismutase Sod1p

LYS9

3.7

13

10.7

Saccharopine dehydrogenase (NADP+, L-glutamate forming) (saccharopine reductase), seventh step in lysine biosynthesis pathway

MAC1

0.7

17

1.4

Transcription factor involved in induction of genes required for reduction and utilization of iron and copper

MAD1

0.7

28

1

Coiled-coil protein involved in spindle-assembly checkpoint, required for cell cycle delay in response to impaired kinetochore function

MAD2

1.0

15

2.4

Spindle-assembly checkpoint protein

MAD3

0.2

16

0.4

Spindle-assembly checkpoint protein required for cell cycle delay in response to impaired kinetochore function

MAF1

0.8

17

1.7

Protein required for sorting of Mod5p

MAG1

0.3

14

0.9

DNA-3-methyladenine glycosidase; excises 3-methyladenine, 7-methyladenine, 7-methylguanine and 7-methylguanine from alkylation-damaged DNA

MAK10

0.2

#N/A-nc

#N/A

Glucose-repressible protein required for replication of double-stranded RNA (dsRNA) virus

MAK11

1.8

11

6.1

Protein essential for replication of M double-stranded RNA (dsRNA) virus, member of the WD (WD-40) repeat family

MAK16

2.5

10

9.6

Nuclear protein with HMG-like acidic region, required for propagation of M1 double-stranded RNA

MAK3

1.8

16

4.1

Protein N-acetyltransferase, acetylates N-terminus of L-A virus GAG protein

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