Positive and Negative Effects

 

Depletion of Histone H4 Results in Gene Expression Increasing and Decreasing from a Subset of Genes

 

The left part of the above figure depicts the transcription level of all of the genes for which data could be collected over the histone depletion time course. The right part of the figure is an enlargement of the indicated region from the left part of the figure. Red coloring indicates that the transcription level of the gene increases when histones are depleted for a given period of time, whereas green coloring indicates that the transcriptional level has decreased. The genes whose expression increases are grouped together and genes whose expression decreases are grouped together. This figure was produced using the TreeView program (19).